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Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts

Identifieur interne : 005D39 ( Main/Exploration ); précédent : 005D38; suivant : 005D40

Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts

Auteurs : Dedee F. Murrell [Australie] ; Benjamin S. Daniel [Australie] ; Pascal Joly [France] ; Luca Borradori [France] ; Masayuki Amagai [Japon] ; Takashi Hashimoto [Japon] ; Frederic Caux [France] ; Branka Marinovic [Serbie] ; Animesh A. Sinha [États-Unis] ; Michael Hertl [Afrique du Sud] ; Philippe Bernard ; David Sirois [États-Unis] ; Giuseppe Cianchini [Italie] ; Janet A. Fairley [États-Unis] ; Marcel F. Jonkman [Allemagne] ; Amit G. Pandya [États-Unis] ; David Rubenstein [États-Unis] ; Detlef Zillikens [États-Unis] ; Aimee S. Payne [États-Unis] ; David Woodley [États-Unis] ; Giovanna Zambruno [Italie] ; Valeria Aoki [États-Unis] ; Carlo Pincelli [États-Unis] ; Luis Diaz [États-Unis] ; Russell P. Hall [États-Unis] ; Michael Meurer [Allemagne] ; Jose M. Jr Mascaro [Espagne] ; Enno Schmidt [États-Unis] ; Hiroshi Shimizu [Japon] ; John Zone ; Robert Swerlick ; Daniel Mimouni ; Donna Culton [États-Unis] ; Jasna Lipozencic [Serbie] ; Benjamin Bince ; Sergei A. Grando ; Jean-Claude Bystryn ; Victoria P. Werth [États-Unis]

Source :

RBID : Pascal:12-0153002

Descripteurs français

English descriptors

Abstract

Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.


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Le document en format XML

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<name sortKey="Schmidt, Enno" sort="Schmidt, Enno" uniqKey="Schmidt E" first="Enno" last="Schmidt">Enno Schmidt</name>
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<name sortKey="Zone, John" sort="Zone, John" uniqKey="Zone J" first="John" last="Zone">John Zone</name>
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<s1>Department of Dermatology, University of Pennsylvania</s1>
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<title xml:lang="en" level="a">Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts</title>
<author>
<name sortKey="Murrell, Dedee F" sort="Murrell, Dedee F" uniqKey="Murrell D" first="Dedee F." last="Murrell">Dedee F. Murrell</name>
<affiliation wicri:level="3">
<inist:fA14 i1="01">
<s1>Department of Dermatology at St George Hospital, University of New South Wales</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Daniel, Benjamin S" sort="Daniel, Benjamin S" uniqKey="Daniel B" first="Benjamin S." last="Daniel">Benjamin S. Daniel</name>
<affiliation wicri:level="3">
<inist:fA14 i1="01">
<s1>Department of Dermatology at St George Hospital, University of New South Wales</s1>
<s2>Sydney</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName>
<settlement type="city">Sydney</settlement>
<region type="état">Nouvelle-Galles du Sud</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Joly, Pascal" sort="Joly, Pascal" uniqKey="Joly P" first="Pascal" last="Joly">Pascal Joly</name>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>Clinique Dermatologique, Institut National de la Santé et de la Recherche Médicale (INSERM), INSERM U905, Rouen University Hospital, Dermatology Department, Rouen University Hospital, University of Rouen</s1>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>University of Rouen</wicri:noRegion>
<wicri:noRegion>Clinique Dermatologique, Institut National de la Santé et de la Recherche Médicale (INSERM), INSERM U905, Rouen University Hospital, Dermatology Department, Rouen University Hospital, University of Rouen</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Borradori, Luca" sort="Borradori, Luca" uniqKey="Borradori L" first="Luca" last="Borradori">Luca Borradori</name>
<affiliation wicri:level="1">
<inist:fA14 i1="03">
<s1>Department of Dermatology, University Hospital of Bern</s1>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>University Hospital of Bern</wicri:noRegion>
<wicri:noRegion>Department of Dermatology, University Hospital of Bern</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Amagai, Masayuki" sort="Amagai, Masayuki" uniqKey="Amagai M" first="Masayuki" last="Amagai">Masayuki Amagai</name>
<affiliation wicri:level="3">
<inist:fA14 i1="04">
<s1>Keio University School of Medicine</s1>
<s2>Tokyo</s2>
<s3>JPN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<placeName>
<settlement type="city">Tokyo</settlement>
<region type="région">Région de Kantō</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Hashimoto, Takashi" sort="Hashimoto, Takashi" uniqKey="Hashimoto T" first="Takashi" last="Hashimoto">Takashi Hashimoto</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Kurume University School of Medicine</s1>
<s3>JPN</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Kurume University School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Caux, Frederic" sort="Caux, Frederic" uniqKey="Caux F" first="Frederic" last="Caux">Frederic Caux</name>
<affiliation wicri:level="3">
<inist:fA14 i1="06">
<s1>Department of Dermatology, University of Paris XIII</s1>
<s2>Bobigny</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Bobigny</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Marinovic, Branka" sort="Marinovic, Branka" uniqKey="Marinovic B" first="Branka" last="Marinovic">Branka Marinovic</name>
<affiliation wicri:level="1">
<inist:fA14 i1="07">
<s1>Department of Dermatology and Venereology, Zagreb University Hospital Center and School of Medicine</s1>
<s3>SRB</s3>
<sZ>8 aut.</sZ>
<sZ>34 aut.</sZ>
</inist:fA14>
<country>Serbie</country>
<wicri:noRegion>Department of Dermatology and Venereology, Zagreb University Hospital Center and School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Sinha, Animesh A" sort="Sinha, Animesh A" uniqKey="Sinha A" first="Animesh A." last="Sinha">Animesh A. Sinha</name>
<affiliation wicri:level="2">
<inist:fA14 i1="08">
<s1>Department of Dermatology, State University of New York at Buffalo</s1>
<s2>Buffalo, New York</s2>
<s3>USA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Hertl, Michael" sort="Hertl, Michael" uniqKey="Hertl M" first="Michael" last="Hertl">Michael Hertl</name>
<affiliation wicri:level="1">
<inist:fA14 i1="09">
<s1>Department of Dermatology, University Hospital</s1>
<s2>Marburg</s2>
<s3>ZAF</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Afrique du Sud</country>
<wicri:noRegion>Marburg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Bernard, Philippe" sort="Bernard, Philippe" uniqKey="Bernard P" first="Philippe" last="Bernard">Philippe Bernard</name>
</author>
<author>
<name sortKey="Sirois, David" sort="Sirois, David" uniqKey="Sirois D" first="David" last="Sirois">David Sirois</name>
<affiliation wicri:level="1">
<inist:fA14 i1="10">
<s1>Department of Oral Medicine, New York University College of Dentistry</s1>
<s3>USA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Oral Medicine, New York University College of Dentistry</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Cianchini, Giuseppe" sort="Cianchini, Giuseppe" uniqKey="Cianchini G" first="Giuseppe" last="Cianchini">Giuseppe Cianchini</name>
<affiliation wicri:level="1">
<inist:fA14 i1="11">
<s1>Immunodermatology Departmentand</s1>
<s3>ITA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Immunodermatology Departmentand</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fairley, Janet A" sort="Fairley, Janet A" uniqKey="Fairley J" first="Janet A." last="Fairley">Janet A. Fairley</name>
<affiliation wicri:level="1">
<inist:fA14 i1="13">
<s1>Departments of Dermatology, University of Iowa and Department of Veterans Affairs Medical Center Iowa City</s1>
<s3>USA</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Departments of Dermatology, University of Iowa and Department of Veterans Affairs Medical Center Iowa City</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Jonkman, Marcel F" sort="Jonkman, Marcel F" uniqKey="Jonkman M" first="Marcel F." last="Jonkman">Marcel F. Jonkman</name>
<affiliation wicri:level="4">
<inist:fA14 i1="14">
<s1>University Medical Center Groningen, University of Groningen</s1>
<s3>DEU</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName>
<settlement type="city">Groningue (ville)</settlement>
<region>Groningue (province)</region>
</placeName>
<orgName type="university">Université de Groningue</orgName>
</affiliation>
</author>
<author>
<name sortKey="Pandya, Amit G" sort="Pandya, Amit G" uniqKey="Pandya A" first="Amit G." last="Pandya">Amit G. Pandya</name>
<affiliation wicri:level="1">
<inist:fA14 i1="15">
<s1>University of Texas Southwestern Medical Center</s1>
<s3>USA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>University of Texas Southwestern Medical Center</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Rubenstein, David" sort="Rubenstein, David" uniqKey="Rubenstein D" first="David" last="Rubenstein">David Rubenstein</name>
<affiliation wicri:level="1">
<inist:fA14 i1="16">
<s1>Department of Dermatology, University of North Carolina</s1>
<s2>Chapel Hill</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>24 aut.</sZ>
<sZ>33 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Zillikens, Detlef" sort="Zillikens, Detlef" uniqKey="Zillikens D" first="Detlef" last="Zillikens">Detlef Zillikens</name>
<affiliation wicri:level="1">
<inist:fA14 i1="17">
<s1>Department of Dermatology, University of Luebeck</s1>
<s3>USA</s3>
<sZ>18 aut.</sZ>
<sZ>28 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Dermatology, University of Luebeck</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Payne, Aimee S" sort="Payne, Aimee S" uniqKey="Payne A" first="Aimee S." last="Payne">Aimee S. Payne</name>
<affiliation wicri:level="1">
<inist:fA14 i1="19">
<s1>Department of Dermatology, University of Pennsylvania</s1>
<s3>USA</s3>
<sZ>19 aut.</sZ>
<sZ>38 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Dermatology, University of Pennsylvania</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Woodley, David" sort="Woodley, David" uniqKey="Woodley D" first="David" last="Woodley">David Woodley</name>
<affiliation wicri:level="4">
<inist:fA14 i1="18">
<s1>Department of Dermatology, Keck School of Medicine, University of Southern California</s1>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<settlement type="city">Los Angeles</settlement>
<region type="state">Californie</region>
</placeName>
<orgName type="university">Université de Californie du Sud</orgName>
</affiliation>
</author>
<author>
<name sortKey="Zambruno, Giovanna" sort="Zambruno, Giovanna" uniqKey="Zambruno G" first="Giovanna" last="Zambruno">Giovanna Zambruno</name>
<affiliation wicri:level="3">
<inist:fA14 i1="12">
<s1>Laboratory of Molecular and Cell Biology,Instituto Dermopatico dell'Immacolata, Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS) IRCCS</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<placeName>
<settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Aoki, Valeria" sort="Aoki, Valeria" uniqKey="Aoki V" first="Valeria" last="Aoki">Valeria Aoki</name>
<affiliation wicri:level="4">
<inist:fA14 i1="20">
<s1>Department of Dermatology, University of Sao Paulo</s1>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName>
<settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author>
<name sortKey="Pincelli, Carlo" sort="Pincelli, Carlo" uniqKey="Pincelli C" first="Carlo" last="Pincelli">Carlo Pincelli</name>
<affiliation wicri:level="1">
<inist:fA14 i1="21">
<s1>Institute of Dermatology, School of Biosciences and Biotechnologies, University of Modena and Reggio Emilia</s1>
<s3>USA</s3>
<sZ>23 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Institute of Dermatology, School of Biosciences and Biotechnologies, University of Modena and Reggio Emilia</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Diaz, Luis" sort="Diaz, Luis" uniqKey="Diaz L" first="Luis" last="Diaz">Luis Diaz</name>
<affiliation wicri:level="1">
<inist:fA14 i1="16">
<s1>Department of Dermatology, University of North Carolina</s1>
<s2>Chapel Hill</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>24 aut.</sZ>
<sZ>33 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Hall, Russell P" sort="Hall, Russell P" uniqKey="Hall R" first="Russell P." last="Hall">Russell P. Hall</name>
<affiliation wicri:level="1">
<inist:fA14 i1="22">
<s1>Division of Dermatology, Duke Medical Center</s1>
<s2>Durham</s2>
<s3>USA</s3>
<sZ>25 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Durham</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Meurer, Michael" sort="Meurer, Michael" uniqKey="Meurer M" first="Michael" last="Meurer">Michael Meurer</name>
<affiliation wicri:level="1">
<inist:fA14 i1="24">
<s1>Carl Gustav Carus Medical School, Dresden University of Technology"</s1>
<s3>DEU</s3>
<sZ>26 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Dresden University of Technology"</wicri:noRegion>
<wicri:noRegion>Carl Gustav Carus Medical School, Dresden University of Technology"</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Mascaro, Jose M Jr" sort="Mascaro, Jose M Jr" uniqKey="Mascaro J" first="Jose M. Jr" last="Mascaro">Jose M. Jr Mascaro</name>
<affiliation wicri:level="1">
<inist:fA14 i1="25">
<s1>Department of Dermatology, University of Barcelona</s1>
<s3>ESP</s3>
<sZ>27 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<wicri:noRegion>Department of Dermatology, University of Barcelona</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Schmidt, Enno" sort="Schmidt, Enno" uniqKey="Schmidt E" first="Enno" last="Schmidt">Enno Schmidt</name>
<affiliation wicri:level="1">
<inist:fA14 i1="17">
<s1>Department of Dermatology, University of Luebeck</s1>
<s3>USA</s3>
<sZ>18 aut.</sZ>
<sZ>28 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Dermatology, University of Luebeck</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Shimizu, Hiroshi" sort="Shimizu, Hiroshi" uniqKey="Shimizu H" first="Hiroshi" last="Shimizu">Hiroshi Shimizu</name>
<affiliation wicri:level="1">
<inist:fA14 i1="23">
<s1>Department of Dermatology, Hokkaido University Graduate School of Medicine</s1>
<s2>Sapporo</s2>
<s3>JPN</s3>
<sZ>29 aut.</sZ>
</inist:fA14>
<country>Japon</country>
<wicri:noRegion>Sapporo</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Zone, John" sort="Zone, John" uniqKey="Zone J" first="John" last="Zone">John Zone</name>
</author>
<author>
<name sortKey="Swerlick, Robert" sort="Swerlick, Robert" uniqKey="Swerlick R" first="Robert" last="Swerlick">Robert Swerlick</name>
</author>
<author>
<name sortKey="Mimouni, Daniel" sort="Mimouni, Daniel" uniqKey="Mimouni D" first="Daniel" last="Mimouni">Daniel Mimouni</name>
</author>
<author>
<name sortKey="Culton, Donna" sort="Culton, Donna" uniqKey="Culton D" first="Donna" last="Culton">Donna Culton</name>
<affiliation wicri:level="1">
<inist:fA14 i1="16">
<s1>Department of Dermatology, University of North Carolina</s1>
<s2>Chapel Hill</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
<sZ>24 aut.</sZ>
<sZ>33 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Chapel Hill</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Lipozencic, Jasna" sort="Lipozencic, Jasna" uniqKey="Lipozencic J" first="Jasna" last="Lipozencic">Jasna Lipozencic</name>
<affiliation wicri:level="1">
<inist:fA14 i1="07">
<s1>Department of Dermatology and Venereology, Zagreb University Hospital Center and School of Medicine</s1>
<s3>SRB</s3>
<sZ>8 aut.</sZ>
<sZ>34 aut.</sZ>
</inist:fA14>
<country>Serbie</country>
<wicri:noRegion>Department of Dermatology and Venereology, Zagreb University Hospital Center and School of Medicine</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Bince, Benjamin" sort="Bince, Benjamin" uniqKey="Bince B" first="Benjamin" last="Bince">Benjamin Bince</name>
</author>
<author>
<name sortKey="Grando, Sergei A" sort="Grando, Sergei A" uniqKey="Grando S" first="Sergei A." last="Grando">Sergei A. Grando</name>
</author>
<author>
<name sortKey="Bystryn, Jean Claude" sort="Bystryn, Jean Claude" uniqKey="Bystryn J" first="Jean-Claude" last="Bystryn">Jean-Claude Bystryn</name>
</author>
<author>
<name sortKey="Werth, Victoria P" sort="Werth, Victoria P" uniqKey="Werth V" first="Victoria P." last="Werth">Victoria P. Werth</name>
<affiliation wicri:level="1">
<inist:fA14 i1="19">
<s1>Department of Dermatology, University of Pennsylvania</s1>
<s3>USA</s3>
<sZ>19 aut.</sZ>
<sZ>38 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Department of Dermatology, University of Pennsylvania</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
<idno type="ISSN">0190-9622</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Journal of the American Academy of Dermatology</title>
<title level="j" type="abbreviated">J. Am. Acad. Dermatol.</title>
<idno type="ISSN">0190-9622</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Bullous pemphigoid</term>
<term>Definition</term>
<term>Dermatology</term>
<term>Prognosis</term>
<term>Recommendation</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Pemphigoïde bulleuse</term>
<term>Définition</term>
<term>Pronostic</term>
<term>Recommandation</term>
<term>Dermatologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Recommandation</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.</div>
</front>
</TEI>
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<list>
<country>
<li>Afrique du Sud</li>
<li>Allemagne</li>
<li>Australie</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Japon</li>
<li>Serbie</li>
<li>États-Unis</li>
</country>
<region>
<li>Californie</li>
<li>Groningue (province)</li>
<li>Latium</li>
<li>Nouvelle-Galles du Sud</li>
<li>Région de Kantō</li>
<li>État de New York</li>
<li>État de São Paulo</li>
<li>Île-de-France</li>
</region>
<settlement>
<li>Bobigny</li>
<li>Groningue (ville)</li>
<li>Los Angeles</li>
<li>Rome</li>
<li>Sydney</li>
<li>São Paulo</li>
<li>Tokyo</li>
</settlement>
<orgName>
<li>Université de Californie du Sud</li>
<li>Université de Groningue</li>
<li>Université de São Paulo</li>
</orgName>
</list>
<tree>
<noCountry>
<name sortKey="Bernard, Philippe" sort="Bernard, Philippe" uniqKey="Bernard P" first="Philippe" last="Bernard">Philippe Bernard</name>
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